Nociceptor clock genes control excitability and pain perception in a sex- and time-dependent manner
Aurélie Brécier, Courtney A. Bannerman, Yu‐Feng Xie, Christopher Dedek, Amanda M Zacharias, Ciara D. O’Connor, Miller Steven D., Laurel L. Ballantyne, J. Du Bois, Qing Duan, Steven A. Prescott, Nader Ghasemlou
This study shows that clock genes in nociceptors affect pain sensitivity differently in males and females across times of day.
bioRxiv · Apr 7, 2025 · PreprintNeuroscience