Yu‐Feng Xie

This study uses optogenetic stimulation to quantify changes in pain sensitivity in mice, finding that ramped photostimuli are more effective than pulsed stimuli for detecting inflammation and analgesia.

This study shows that clock genes in nociceptors affect pain sensitivity differently in males and females across times of day.

The paper shows that nociceptors can achieve equivalent excitability through different sodium channel subtypes, challenging the effectiveness of subtype-selective analgesic drugs.