Christopher Dedek

The paper introduces Spinotrode, a vertebral implant for long-term single-cell recordings in the dorsal horns of behaving mice, revealing new insights into spinal neuron dynamics during natural behaviors.

The paper shows adaptation in somatosensory afferents improves rate and temporal coding of vibrotactile stimulus features by modulating spiking in different ways.

This study uses optogenetic stimulation to quantify changes in pain sensitivity in mice, finding that ramped photostimuli are more effective than pulsed stimuli for detecting inflammation and analgesia.

This study shows that clock genes in nociceptors affect pain sensitivity differently in males and females across times of day.

This study investigates the coding properties of low-threshold mechanoreceptors in rodent glabrous skin, showing their heterogeneity and how they encode vibrotactile stimuli through rate and temporal coding.

The paper compares NMDA receptor decay kinetics in lamina I pain neurons across sex and species, finding conserved heterogeneity but species-specific differences in subunit contributions.