Author

Jordan E. Bloom

Altius Institute for Biomedical Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:variant calling· 1

Frequent Co-Authors

John A. StamatoyannopoulosiD· 2 shared Matthew S. Wilken· 2 shared Alexander Joel FederationiD· 1 shared Alexandra KirtsouiD· 1 shared Alister P. W. FunnelliD· 1 shared Benjamin P. Van Biber· 1 shared Christie CiarloiD· 1 shared Daniel BatesiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersGenomics

John A. StamatoyannopoulosORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Large-scale discovery of potent, compact and lineage specific enhancers for gene therapy vectors

Nikoletta Psatha, Pavel Sova, Grigorios Georgolopoulos, Kiriaki Paschoudi, Mineo Iwata, Jordan E. Bloom, Tatyana Ulyanova, Hao Wang, Alexandra Kirtsou, Ninos-Ioannis Vasiloudis, Matthew S. Wilken, John A. Stamatoyannopoulos, Evangelia Yannaki, Thalia Papayannopoulou, George Stamatoyannopoulos, Jeff D. Vierstra

The paper identifies potent, compact, and lineage-specific enhancers for gene therapy vectors using epigenomic data and validates their efficacy in correcting a thalassemia phenotype.

bioRxiv · Oct 4, 2023 · PreprintGenomics

Quantitative dialing of gene expression via precision targeting of KRAB repressor

Matthew S. Wilken, Christie Ciarlo, Jocelynn R. Pearl, Elaine V. Schanzer, Hanna Liao, Benjamin P. Van Biber, Konstantin Queitsch, Jordan E. Bloom, Alexander Joel Federation, Reyes Acosta, Shinny Vong, Ericka Otterman, Douglas Dunn, Hao Wang, Pavel Zrazhevskiy, , John A. Stamatoyannopoulos

This study demonstrates precise control of gene expression levels by targeting the KRAB repressor domain in human cells.

bioRxiv · Feb 19, 2020 · PreprintSynthetic Biology