Cardiac stress leads to regulation of Filamin C dimerisation via an ancient phosphorylation-modulated interaction with HSPB7
Zihao Wang, Guodong Cao, Miranda P. Collier, Xingyu Qiu, Sophie Broadway‐Stringer, Dominik Šaman, Jediael Z. Y. Ng, Navoneel Sen, Amar J. Azad, Charlotte L. Hooper, Johannes P. Zimmermann, M.A. McDonough, Jürgen Brem, Patrick Rabe, Haigang Song, , Justin L. P. Benesch
The paper investigates how cardiac stress regulates Filamin C dimerisation through phosphorylation-modulated interactions with HSPB7, revealing evolutionary conservation of this mechanism.
bioRxiv · Jan 5, 2024 · PreprintMolecular Biology