The multimerization pathway of the glucocorticoid receptor
Andrea Alegre‐Martí, Alba Jiménez‐Panizo, Agustina L. Lafuente, Thomas A. Johnson, Inés Montoya-Novoa, Maria Nuria Peralta-Moreno, Pilar Montanyà-Valluguera, Josep Ponsetí-Pons, Montserrat Abella, Sohyoung Kim, Mireia Díaz, Marta Vilaseca, Paloma Pérez, Juan Fernández‐Recio, J. Rubio, , Eva Estébanez‐Perpiñá
The paper presents a new crystal structure of agonist-bound GR-LBD and proposes a model for GR multimerization, reconciling structural and functional data on glucocorticoid resistance.
Nucleic Acids Research · Sep 18, 2025Peer-reviewedBiochemistry