Author
Universitat de BarcelonaORCID 0000-0002-5529-2325Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Andrea Alegre‐Martí, Alba Jiménez‐Panizo, Agustina L. Lafuente…·Eva Estébanez‐Perpiñá
The paper presents a new crystal structure of agonist-bound GR-LBD and proposes a model for GR multimerization, reconciling structural and functional data on glucocorticoid resistance.
Erika Zodda, Mònica Pons, Natàlia DeMoya‐Valenzuela…·Timothy M. Thomson
This study shows that SARS-CoV-2's ORF9b protein activates inflammasomes and caspase-1, and small molecules inhibiting its homodimerization reduce inflammation and restore interferon signaling.
José M. Granadino‐Roldán, Antonia S. J. S. Mey, Juan J. Pérez González…·Julien Michel
The paper evaluates setup protocols for alchemical free energy calculations on ACK1 inhibitors, finding that manual placement of a bridging water molecule significantly improves accuracy.