Human Endogenous Retrovirus Expression is Dynamically Regulated in Parkinson's Disease
Juozas Gordevičius, Thomas M. Goralski, Alexis L. Bergsma, Andrea Parham, Emily Kuhn, Lindsay K. Meyerdirk, Mitch McDonald, Milda Milčiūtė, Elizabeth I. van Putten, Lee L. Marshall, Patrik Brundin, Lena Brundin, Viviane Labrie, Michael X. Henderson, John Andrew Pospisilik
This study identifies up-regulation of human endogenous retrovirus (HERV) transcripts in Parkinson's disease (PD) across multiple tissues and blood, linking TE activation to PD pathogenesis and potential treatment monitoring.
bioRxiv · Nov 3, 2023 · PreprintNeuroscience