Lena Brundin

This study shows chronic H. pylori infection causes brain inflammation and dopaminergic neuron loss through inflammation, independent of α-synuclein pathology, and eradication reduces these effects.

The paper examines alpha-synuclein aggregation and molecular changes in appendix tissues from synucleinopathy patients compared to controls.

This study profiles DNA methylation in COVID-19 patients and finds hypomethylation linked to neurological pathways in severe cases.

This study examines how changes in kynurenine pathway metabolite ratios relate to antidepressant response in patients treated with SSRIs, finding specific shifts in neuroprotective-to-neurotoxic metabolite balances.

The paper identifies that Tet2 loss promotes ciliogenesis and reduces α-synuclein pathology in Parkinson's disease models.

This study identifies up-regulation of human endogenous retrovirus (HERV) transcripts in Parkinson's disease (PD) across multiple tissues and blood, linking TE activation to PD pathogenesis and potential treatment monitoring.

The paper finds increased levels of neurotoxic metabolites in mild COVID-19 patients, associated with inflammation and hypertension.

This study shows that T cells reduce phosphorylated α-synuclein pathology in a mouse model of α-synucleinopathy.

This study identifies elevated toxic bile acids in Parkinson's disease patients and links them to gut microbiome dysbiosis and early biliary changes.