Author

Mohammad Zeineddine

The University of Texas MD Anderson Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Abhinav K. JainiD· 1 shared Aviad Ben‐ShmueliD· 1 shared Chaohao LiiD· 1 shared Chi Yin ChingiD· 1 shared Denise J. SpringiD· 1 shared Fadl A. ZeineddineiD· 1 shared Jiexi LiiD· 1 shared Jingjing Liu· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Abhinav K. JainORCID

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1 paper

Recent·Most cited

The Y chromosome gene KDM5D restrains CD8+ T cell antitumor immunity through TCR and cholesterol-exhaustion programs

Jiexi Li, Chi Yin Ching, Aviad Ben‐Shmuel, Paulino Tallón de Lara, Jingjing Liu, Shan Jiang, Chaohao Li, Ziyuan Zhang, William Huaiyang Wu, Max Slotnik, Xiaotian Wang, Raul Caballero Montes, Abhinav K. Jain, Nicholas J. Hornstein, Fadl A. Zeineddine, , Ronald Anthony DePinho

This study identifies KDM5D on the Y chromosome as a suppressor of CD8+ T cell antitumor immunity in males, linking it to TCR and cholesterol-exhaustion programs.

bioRxiv · Sep 1, 2026 · PreprintCancer Biology