Author

Max Slotnik

Duke University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Abhinav K. JainiD· 1 shared Alexander L. HaniD· 1 shared Aviad Ben‐ShmueliD· 1 shared Chaohao LiiD· 1 shared Chi Yin ChingiD· 1 shared David A. FoxiD· 1 shared Denise J. SpringiD· 1 shared Fadl A. ZeineddineiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Abhinav K. JainORCID

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2 papers

Recent·Most cited

Genome-scale perturbation signatures from primary human CD4+ T cells improve genetics-based prioritization of immune drug targets

Alexander L. Han, Max Slotnik, David A. Fox, Ryan S. Dhindsa, Johann Eli Gudjonsson, Joanne Michelle Kahlenberg, Joshua D. Welch

The paper introduces IGNITE, a framework that combines genetic data with functional genomics to prioritize immune drug targets, showing improved performance over genetic methods alone.

bioRxiv · Sep 16, 2026 · PreprintBioinformatics

The Y chromosome gene KDM5D restrains CD8+ T cell antitumor immunity through TCR and cholesterol-exhaustion programs

Jiexi Li, Chi Yin Ching, Aviad Ben‐Shmuel, Paulino Tallón de Lara, Jingjing Liu, Shan Jiang, Chaohao Li, Ziyuan Zhang, William Huaiyang Wu, Max Slotnik, Xiaotian Wang, Raul Caballero Montes, Abhinav K. Jain, Nicholas J. Hornstein, Fadl A. Zeineddine, , Ronald Anthony DePinho

This study identifies KDM5D on the Y chromosome as a suppressor of CD8+ T cell antitumor immunity in males, linking it to TCR and cholesterol-exhaustion programs.

bioRxiv · Sep 1, 2026 · PreprintCancer Biology