Differential effects of immobilized CCL21 and ICAM1 on TILs with distinct expansion properties
Sofi Yado, Rawan Zoabi, Karin Brezinger-Dayan, Shira Albeck, Tamar Unger, Moran Meiron, Galit Eisenberg, Alessio David Nahmad, Aya Tzur Gilat, Michal Judith Besser, Benjamin Geiger
This study identifies markers distinguishing TIL expansion properties and develops SIN-based strategies to enhance expansion and activation of both low- and high-expanding TILs.
Frontiers in Immunology · Oct 3, 2025Peer-reviewedBioengineering