A Lymphomimetic Synthetic Immune Niche, Consisting of CCL21 and ICAM1, Accelerates the Expansion of Potent CAR T-cells
Karin Brezinger-Dayan, Sofi Yado, Rawan Zoabi, Benjamin Geiger, Michal Judith Besser
This paper shows that a synthetic immune niche with CCL21 and ICAM1 boosts CAR T-cell expansion and potency, increasing cell yield and CAR T-cell frequency.
bioRxiv · Sep 3, 2026 · PreprintImmunology