Sofi Yado

This study identifies that a synthetic immune niche enhances T cell cytotoxicity by accelerating lytic hit delivery, not by increasing target encounters or conjugate stability.

This paper shows that a synthetic immune niche with CCL21 and ICAM1 boosts CAR T-cell expansion and potency, increasing cell yield and CAR T-cell frequency.

This study identifies markers distinguishing TIL expansion properties and develops SIN-based strategies to enhance expansion and activation of both low- and high-expanding TILs.

This study investigates how a synthetic immune niche modulates T-cell proliferation and cytotoxicity, finding that these properties are negatively correlated and differentially regulated by activation mode.