Knock-in = knock-out: differential fitness effects of cardinal mutations in Anopheles stephensi
Mireia Larrosa‐Godall, Lewis Shackleford, Philip T. Leftwich, Estela González, Joshua X. D. Ang, Matthew Edwards, Katherine Nevard, James C. Y. Luk, Morgan Mckee, Rob J. Noad, Michelle A. E. Anderson, Luke Alphey
The paper investigates fitness differences between knock-in and knock-out cd mutants in Anopheles stephensi, finding that knock-in mutants have reduced survival and midgut dysfunction, while knock-outs do not.
bioRxiv · Jul 9, 2026 · PreprintGenetics