Chitinase-3-like 1 regulates TH2 cells, TFH cells and IgE following helminth infection
M. L. Curtiss, A. F. Rosenberg, C. D. Scharer, N. A. B. Benavides, J. E. Bradley, B. Leon, C. C. Steele, T. D. Randall, F. E. Lund
This study shows that ChI3L1 is required for TH2, TFH, and IgE responses following helminth infection and vaccination, but not for IgG1 responses.
bioRxiv · Sep 26, 2022 · PreprintImmunology