Thermoneutral housing does not accelerate metabolic dysfunction-associated fatty liver disease in male or female mice fed a Western diet
J. R. Nunes, T. K. Smith, P. Ghorbani, C. O'Dwyer, N. A. Trzaskalski, H. Dergham, C. Pember, M. K. Kilgour, E. E. Mulvihill, M. D. Fullerton
This study investigates whether thermoneutral housing accelerates MAFLD in mice fed a Western diet, finding no significant acceleration in disease progression despite sex-specific metabolic effects.
bioRxiv · Jan 24, 2023 · PreprintPhysiology