Author

C. Pember

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

C. O'Dwyer· 2 shared J. R. Nunes· 2 shared M. D. Fullerton· 2 shared M. K. Kilgour· 2 shared P. Ghorbani· 2 shared T. K. Smith· 2 shared A. Blais· 1 shared B. Lacoste· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersPhysiology

C. O'Dwyer

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Thermoneutral housing does not accelerate metabolic dysfunction-associated fatty liver disease in male or female mice fed a Western diet

J. R. Nunes, T. K. Smith, P. Ghorbani, C. O'Dwyer, N. A. Trzaskalski, H. Dergham, C. Pember, M. K. Kilgour, E. E. Mulvihill, M. D. Fullerton

This study investigates whether thermoneutral housing accelerates MAFLD in mice fed a Western diet, finding no significant acceleration in disease progression despite sex-specific metabolic effects.

bioRxiv · Jan 24, 2023 · PreprintPhysiology

Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection

P. Ghorbani, S. Y. Kim, T. K. Smith, L. Minarrieta, V. Robert-Gostlin, M. K. Kilgour, M. Ilijevska, I. Alecu, S. A. Snider, K. D. Margison, J. R. Nunes, D. Woo, C. Pember, C. O'Dwyer, J. Ouellette, , M. D. Fullerton

This study shows that choline metabolism is essential for IL-4-induced macrophage polarization and RELMα expression during helminth infection, affecting immune homeostasis and parasite clearance.

bioRxiv · Sep 30, 2022 · PreprintImmunology