Chloride ions evoke taste sensations by binding to the extracellular ligand-binding domain of sweet/umami taste receptors
N. Atsumi, K. Yasumatsu, Y. Takashina, C. Ito, N. Yasui, R. Margolskee, A. Yamashita
The paper shows chloride ions bind to sweet/umami taste receptors, inducing conformational changes and contributing to salt taste perception.
bioRxiv · Feb 23, 2022Biophysics