A. Yamashita

This paper investigates the localization of factor XI in human deep vein thrombus and evaluates the effects of FXIa and FXa inhibitors on venous thrombus formation and hemostasis in rabbits.

The paper uses accelerated molecular dynamics and AlphaFold2 to identify a missing inward-open conformation of the OxlT transporter protein.

This study identifies CB1 receptor antagonists as inhibitors of Lujo virus entry by suppressing viral membrane fusion and reducing infectivity in vitro.

The paper investigates the effects of LONP2 depletion on peroxisomal function and cholesterol metabolism, revealing cell-type-specific responses and implications for peroxisomal disorders.

This paper establishes a reproducible murine pulmonary embolism model using small thrombi and evaluates the inflammatory response in the lung.

This paper introduces a hidden Markov model to estimate molecular orientations from HS-AFM time-series data, showing improved robustness compared to frame-by-frame analysis.

The paper shows chloride ions bind to sweet/umami taste receptors, inducing conformational changes and contributing to salt taste perception.

This study determines the crystal structures of OxlT, an oxalate transporter, and reveals its mechanism for selective oxalate uptake and exclusion of other carboxylates.

This study develops mouse monoclonal antibodies against SARS-CoV-2 spike protein that show neutralizing activity and are suitable for immunoassays and large-scale production.

This study shows that HHP-decellularized bovine vascular grafts can be successfully recellularized with recipient cells in a porcine model, preserving ECM and showing patency without anticoagulants.

This study uses differential scanning fluorimetry to analyze amino-acid binding to the T1r2a/T1r3LBD model receptor, showing thermal stabilization and specificity for L-amino acids.