Author

N. Bradshaw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 4 Approach:experimental assay· 4 Research Focus:protein folding & dynamics· 4 Research Focus:chromatin & epigenetic regulation· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

K. Ho· 3 shared R. Baral· 2 shared S. Caban-Penix· 2 shared D. Kern· 1 shared J. B. Hopkins· 1 shared L. A. Calderone· 1 shared M. B. Watkins· 1 shared M. Hoemberger· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBiochemistry

K. Ho

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Author profile →

4 papers

Recent·Most cited

Docking interactions determine substrate specificity of members of a widespread family of protein phosphatases

S. Caban-Penix, K. Ho, W. Yang, R. Baral, N. Bradshaw

The paper identifies a conserved substrate docking interface in PPM phosphatases that determines substrate specificity through allosteric regulation.

bioRxiv · May 3, 2024Biochemistry

A General Mechanism for Initiating the General Stress Response in Bacteria

R. Baral, K. Ho, R. P. Kumar, J. B. Hopkins, M. B. Watkins, S. LaRussa, S. Caban-Penix, L. A. Calderone, N. Bradshaw

The paper identifies a coiled-coil linker mechanism in RsbU that activates the General Stress Response in bacteria by transducing signals from sensor domains.

bioRxiv · Feb 16, 2024Microbiology

From primordial clocks to circadian oscillators

W. Pitsawong, R. A. Padua, T. Grant, M. Hoemberger, R. Otten, N. Bradshaw, N. Grigorieff, D. Kern

This study investigates the primordial circadian clock in Rhodobacter sphaeroides using structural and kinetic analyses to elucidate its mechanism and evolutionary origins.

bioRxiv · Nov 28, 2022Biochemistry

A conserved regulatory switch controls phosphatase activity and specificity

K. Ho, N. Bradshaw

The paper identifies a conserved regulatory switch in PP2C phosphatases that controls activity and substrate specificity through metal cofactor binding and regulatory input integration.

bioRxiv · Sep 27, 2019 · PreprintBiochemistry