Author

R. Baral

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 2 Bioengineering· 1 Cancer Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:proteomics· 3 Organism:bacteria (other)· 2 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:protein folding & dynamics· 2

Frequent Co-Authors

K. Ho· 2 shared N. Bradshaw· 2 shared S. Caban-Penix· 2 shared A. Anaya-Sanchez· 1 shared A. Balakhmet· 1 shared A. Bhuniya· 1 shared A. Bose· 1 shared A. Saha· 1 shared

Activity by Year

2018-2024 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBiochemistry

K. Ho

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Docking interactions determine substrate specificity of members of a widespread family of protein phosphatases

S. Caban-Penix, K. Ho, W. Yang, R. Baral, N. Bradshaw

The paper identifies a conserved substrate docking interface in PPM phosphatases that determines substrate specificity through allosteric regulation.

bioRxiv · May 3, 2024Biochemistry

Experimental type 1 diabetes metabolically rejuvenates CD8+ T cells for improved control of tumor growth through an IGF1-IGF1R axis

A. Sarkar, S. Dhar, S. Bera, M. Chakravarti, A. Verma, P. Prasad, J. Sultana, J. Das, A. Saha, A. Bhuniya, I. Guha, S. Dasgupta, S. S. Roy, S. Banerjee, S. Roy, , A. Bose

This study shows that experimental type 1 diabetes enhances CD8+ T cell function via the IGF1-IGF1R axis, leading to better tumor control.

bioRxiv · Apr 4, 2024 · PreprintCancer Biology

Transcriptomics and trans-organellar complementation reveal a limited signaling capacity of 12-cis-oxo-phytodienoic acid in wounded Arabidopsis

K. Mekkaoui, R. Baral, F. Smith, M. Klein, I. Feussner, B. Hause

The paper investigates OPDA signaling in Arabidopsis by comparing transcriptomes of mutants and applying OPDA externally, finding limited signaling capacity and compartmentalization of endogenous OPDA.

bioRxiv · Mar 22, 2024Plant Biology

Forage conservation is a neglected nitrous oxide source

S. Yang, M. Mahmood, R. Baral, H. Wu, M. Almloff, L. Stanton, D. Min, B. Smiley, C. Liams, J. Yu, J. Im

This study investigates N2O emissions from forage conservation and finds it could be a significant source, with chlorate reducing emissions but other factors having no effect.

bioRxiv · Mar 19, 2024Bioengineering

A General Mechanism for Initiating the General Stress Response in Bacteria

R. Baral, K. Ho, R. P. Kumar, J. B. Hopkins, M. B. Watkins, S. LaRussa, S. Caban-Penix, L. A. Calderone, N. Bradshaw

The paper identifies a coiled-coil linker mechanism in RsbU that activates the General Stress Response in bacteria by transducing signals from sensor domains.

bioRxiv · Feb 16, 2024Microbiology

Impaired aldehyde detoxification caused by a common human polymorphism promotes anti-bacterial immunity

S. Espich, S. Berry, X. Chang, A. Balakhmet, N. T. T. Thuong, R. Dorajoo, C. C. Khor, C. K. Heng, J.-M. Yuan, W.-P. Koh, D. Fox, A. Anaya-Sanchez, L. Tenney, C. J. Chang, R. Baral, , S. A. Stanley

The paper shows ALDH2 deficiency enhances anti-bacterial immunity by increasing aldehyde levels that kill pathogens and boost inflammatory responses.

bioRxiv · Aug 24, 2023 · PreprintMicrobiology

Telomere DNA G-quadruplex folding within actively extending human telomerase

L. I. Jansson, J. W. Parks, J. Hentschel, T. R. Chang, R. Baral, C. R. Bagshaw, M. D. Stone

This study investigates how G-quadruplex (GQ) folding of nascent telomere DNA affects telomerase catalysis and dissociation kinetics.

bioRxiv · Oct 26, 2018Biochemistry