Author

N. Christoforou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:genetic perturbation / CRISPR· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

J. Owens· 2 shared A. Healy· 1 shared A. Kowala· 1 shared A. Paredes-Redondo· 1 shared A. Tinker· 1 shared A. Weston· 1 shared C. Morera· 1 shared C. W. Lee· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

J. Owens

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Development and validation of a high throughput screening platform to enable target identification in skeletal muscle cells from Duchenne Muscular Dystrophy (DMD) patients

S. Hariharan, O. Lorintiu, C. W. Lee, E. Duchemin-Pelletier, X. Li, A. Healy, R. Doyonnas, L. Selig, P. Poydenot, E. Ventre, A. Weston, J. Owens, N. Christoforou

The paper develops and validates a high throughput screening platform using morphological profiling to predict DMD disease phenotype in patient-derived myotubes.

bioRxiv · May 24, 2023 · PreprintCell Biology

CRISPR-mediated correction of skeletal muscle Ca2+ handling in a novel DMD patient-derived pluripotent stem cell model

C. Morera, J. Kim, A. Paredes-Redondo, M. Nobles, D. Rybin, R. Moccia, A. Kowala, J. Meng, S. Garren, P. Liu, J. E. Morgan, F. Muntoni, N. Christoforou, J. Owens, A. Tinker, Y.-Y. Lin

This study uses CRISPR to correct dystrophin mutations in DMD patient-derived PSCs, revealing impaired Ca2+ handling and showing rescue through gene correction.

bioRxiv · Feb 17, 2022Cell Biology