Author

J. Owens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

N. Christoforou· 2 shared A. Healy· 1 shared A. Kowala· 1 shared A. Paredes-Redondo· 1 shared A. Quattrone· 1 shared A. Tinker· 1 shared A. Weston· 1 shared B. S. Drolet· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

N. Christoforou

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Zea mays genotype influences microbial and viral rhizobiome community structure

P. Yadav, A. Quattrone, Y. Yang, J. Owens, R. Kiat, T. Kuppusamy, S. E. Russo, K. A. Weber

This study shows that different maize genotypes influence the structure of microbial and viral communities in their rhizobiome, with significant differences in viral and microbial abundance and gene content between genotypes.

bioRxiv · Jun 9, 2023Microbiology

Development and validation of a high throughput screening platform to enable target identification in skeletal muscle cells from Duchenne Muscular Dystrophy (DMD) patients

S. Hariharan, O. Lorintiu, C. W. Lee, E. Duchemin-Pelletier, X. Li, A. Healy, R. Doyonnas, L. Selig, P. Poydenot, E. Ventre, A. Weston, J. Owens, N. Christoforou

The paper develops and validates a high throughput screening platform using morphological profiling to predict DMD disease phenotype in patient-derived myotubes.

bioRxiv · May 24, 2023 · PreprintCell Biology

CRISPR-mediated correction of skeletal muscle Ca2+ handling in a novel DMD patient-derived pluripotent stem cell model

C. Morera, J. Kim, A. Paredes-Redondo, M. Nobles, D. Rybin, R. Moccia, A. Kowala, J. Meng, S. Garren, P. Liu, J. E. Morgan, F. Muntoni, N. Christoforou, J. Owens, A. Tinker, Y.-Y. Lin

This study uses CRISPR to correct dystrophin mutations in DMD patient-derived PSCs, revealing impaired Ca2+ handling and showing rescue through gene correction.

bioRxiv · Feb 17, 2022Cell Biology

Susceptibility of midge and mosquito vectors to SARS-CoV-2 by natural route of infection

V. Balaraman, B. S. Drolet, N. N. Gaudreault, W. C. Wilson, J. Owens, D. Bold, D. A. Swanson, D. C. Jasperson, L. E. Noronha, J. A. Richt, D. Mitzel

This study investigates whether biting insects can transmit SARS-CoV-2 after ingesting an infected blood meal, finding no replication in tested species or cell lines.

bioRxiv · Sep 29, 2020Microbiology