Author

N. D. Peterson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Research Focus:host-pathogen & immune response· 4 Approach:experimental assay· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1

Frequent Co-Authors

R. Pukkila-Worley· 4 shared J. E. Salisbury· 2 shared K. A. Wani· 2 shared S. Y. Tse· 2 shared A. L. Page· 1 shared A. Page· 1 shared C. A. Schiffer· 1 shared C. E. Tocheny· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersImmunology

R. Pukkila-Worley

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4 papers

Recent·Most cited

Activation of intestinal immunity by pathogen effector-triggered aggregation of lysosomal TIR-1/SARM1

S. Tse-Kang, K. A. Wani, N. D. Peterson, A. Page, R. Pukkila-Worley

The paper identifies lysosomal TIR-1/SARM1 as a sensor for oxidative stress induced by pathogenic bacteria, activating intestinal immunity in C. elegans.

bioRxiv · Dec 4, 2023 · PreprintImmunology

Transcriptional suppression of sphingolipid catabolism controls pathogen resistance in C. elegans

M. A. Nasrallah, N. D. Peterson, J. E. Salisbury, P. Liu, A. L. Page, S. Y. Tse, K. A. Wani, C. E. Tocheny, R. Pukkila-Worley

The paper identifies NHR-66 as a transcriptional repressor that suppresses sphingolipid catabolism to enhance pathogen resistance in C. elegans.

bioRxiv · Aug 10, 2023 · PreprintImmunology

Bacterial pattern recognition in C. elegans by a nuclear hormone receptor

N. D. Peterson, S. Y. Tse, Q. J. Huang, C. A. Schiffer, R. Pukkila-Worley

The paper identifies NHR-86/HNF4 as a bacterial pattern recognition receptor in C. elegans that detects phenazine-1-carboxamide from Pseudomonas aeruginosa to trigger an anti-pathogen response.

bioRxiv · Jul 12, 2022 · PreprintImmunology

A TIR-1/SARM1 phase transition underlies p38 immune pathway activation in the C. elegans intestine

N. D. Peterson, J. D. Icso, J. E. Salisbury, T. C. Rodriguez, P. Thompson, R. Pukkila-Worley

This paper shows that a phase transition of TIR-1/SARM1 in C. elegans activates the p38 immune pathway, linking protein oligomerization to immune response and pathogen defense.

bioRxiv · Aug 5, 2021Immunology