Author

N. Dos Santos Pacheco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Assay:electronic health records· 1

Frequent Co-Authors

D. Soldati-Favre· 5 shared N. Tosetti· 3 shared B. Maco· 2 shared L. Brusini· 2 shared M. Brochet· 2 shared O. Vadas· 2 shared R. Haase· 2 shared A. Krishnan· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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5 shared papersMicrobiology

D. Soldati-Favre

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

BiochemistrybioRxivJan 23, 2023

Structural and regulatory insights into the glideosome-associated connector from Toxoplasma gondii

A. Kumar, O. Vadas, N. Dos Santos Pacheco…·S. Matthews

This study presents the crystal structure of Toxoplasma gondii GAC and proposes a multi-conformational model for its assembly in the glideosome.

DOI 10.7554/elife.86049

experimental assay

𝕏 PostBluesky

MicrobiologybioRxivJun 6, 2022

Conoid extrusion serves as gatekeeper for entry of glideosome components into the pellicular space to control motility and invasion in Apicomplexa

N. Dos Santos Pacheco, L. Brusini, R. Haase…·D. Soldati-Favre

The paper identifies new components of the conoid in Apicomplexa and shows it regulates glideosome assembly and motility by controlling F-actin flux.

DOI 10.1038/s41564-022-01212-x

experimental assaycell type annotation

𝕏 PostBluesky

MicrobiologybioRxivNov 3, 2021

Organization and composition of apicomplexan kinetochores reveals plasticity in chromosome segregation across parasite modes of division

L. Brusini, N. Dos Santos Pacheco, D. Soldati-Favre, M. Brochet

This study identifies novel kinetochore components in apicomplexan parasites and reveals plasticity in kinetochore composition and chromosome segregation across their lifecycle.

DOI 10.1083/jcb.202111084

proteomicsdeep learning

𝕏 PostBluesky

MicrobiologybioRxivMar 22, 2021

Revisiting the role of Toxoplasma gondii ERK7 in the maintenance and stability of the apical complex

D. Soldati-Favre, N. Dos Santos Pacheco, N. Tosetti…·R. Haase

This paper shows that Toxoplasma gondii ERK7 depletion mimics AC9/AC10 depletion, causing apical complex disorganization and impairing parasite motility and invasion.

DOI 10.1128/mbio.02057-21

humanproteomics

𝕏 PostBluesky

MicrobiologybioRxivFeb 25, 2020

Two alveolin network proteins are essential for the subpellicular microtubules assembly and conoid anchoring to the apical pole of mature Toxoplasma gondii

N. Tosetti, N. Dos Santos Pacheco, E. Bertiaux…·D. Soldati-Favre

This study identifies AC9 and AC10 as essential alveolin network proteins required for SPMT assembly and conoid anchoring in Toxoplasma gondii, with loss of these proteins leading to conoidless mature parasites.

DOI 10.7554/elife.56635

humanelectronic health records

𝕏 PostBluesky