Author

N. I. Edman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:protein structure· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Research Focus:protein design· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Baker· 3 shared D. C. Ekiert· 2 shared G. Bhabha· 2 shared R. L. Redler· 2 shared R. Mout· 2 shared S. Lee· 2 shared Y. Hsia· 2 shared A. Courbet· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersBioengineering

D. Baker

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies

N. I. Edman, R. L. Redler, A. Phal, T. Schlichthaerle, S. R. Srivatsan, A. Etemadi, S. An, A. Favor, D. Ehnes, Z. Li, F. Praetorius, M. Gordon, W. Yang, B. Coventry, D. R. Hicks, , D. Baker

This study designs synthetic oligomeric ligands to modulate FGFR signaling and shows their impact on vascular cell fate decisions.

Cell · Jul 1, 2024Peer-reviewedBioengineering

De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity

R. Mout, R. C. Bretherton, J. Decarreau, S. Lee, N. I. Edman, M. Ahlrichs, Y. Hsia, D. D. Sahtoe, G. Ueda, N. Gregorio, A. Sharma, R. Schulman, C. A. DeForest, D. Baker

This paper designs modular protein hydrogels with tunable viscoelasticity by controlling molecular parameters and demonstrates their use both intra- and extracellularly.

bioRxiv · Jun 2, 2023Bioengineering

Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks

Y. Hsia, R. Mout, W. Sheffler, N. I. Edman, I. Vulovic, Y.-J. Park, R. L. Redler, M. J. Bick, A. K. Bera, A. Courbet, A. Kang, T. Brunette, U. Nattermann, E. Tsai, A. Saleem, , D. Baker

This paper describes a hierarchical method to design multi-scale symmetric protein complexes using repeat proteins and helical bundles, resulting in large symmetric assemblies like an icosahedral nanocage.

bioRxiv · Jul 27, 2020Biochemistry