Author

N. J. Brooks

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Biophysics· 1

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Menny· 1 shared A. P. Joseph· 1 shared B. P. Morgan· 1 shared C. M. Boyd· 1 shared D. Bubeck· 1 shared M. Serna· 1 shared M. Topf· 1 shared S. Gardner· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

A. Menny

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1 paper

Recent·Most cited

CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers

A. Menny, M. Serna, C. M. Boyd, S. Gardner, A. P. Joseph, B. P. Morgan, M. Topf, N. J. Brooks, D. Bubeck

This study uses cryo-EM to show how the complement membrane attack complex interacts with lipid bilayers through distinct mechanisms involving C6/C7 and C8/C9, revealing structural insights into pore formation and membrane disruption.

bioRxiv · Aug 17, 2018Biophysics