Author

B. P. Morgan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:cryo-EM· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Menny· 1 shared A. P. Joseph· 1 shared B. Merrick· 1 shared C. A. Fielding· 1 shared C. Graham· 1 shared C. M. Boyd· 1 shared D. Bubeck· 1 shared E. Crozier· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. Menny

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Complement Regulator Factor H is a Cofactor for Thrombin in both Pro- and Anticoagulant Roles

G. McCluskey, G. E. Davies, R. L. Velounias, T. R. Hughes, B. P. Morgan, R. J. Preston, P. W. Collins, P. V. Jenkins, M. Heurich

This study shows that complement regulator Factor H binds thrombin with high affinity and acts as a cofactor that enhances both pro- and anticoagulant functions of thrombin.

bioRxiv · Jul 22, 2021 · PreprintImmunology

ADNKA overcomes SARS-CoV2-mediated NK cell inhibition through non-spike antibodies

C. A. Fielding, P. Sabberwal, J. C. Williamson, E. J. Greenwood, E. Crozier, W. Zelek, J. Seow, C. Graham, I. Huettner, J. Edgeworth, B. P. Morgan, K. Ladell, M. Eberl, I. R. Humphreys, B. Merrick, , R. J. Stanton

This study identifies ADNKA as a mechanism by which SARS-CoV-2-infected cells evade NK cell inhibition, showing that non-spike antibodies drive sustained NK activation and cytokine production.

bioRxiv · Apr 6, 2021Immunology

CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers

A. Menny, M. Serna, C. M. Boyd, S. Gardner, A. P. Joseph, B. P. Morgan, M. Topf, N. J. Brooks, D. Bubeck

This study uses cryo-EM to show how the complement membrane attack complex interacts with lipid bilayers through distinct mechanisms involving C6/C7 and C8/C9, revealing structural insights into pore formation and membrane disruption.

bioRxiv · Aug 17, 2018Biophysics