Author

N. J. Francis-Newton

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Esposito· 1 shared A. G. Coyne· 1 shared A. R. Bayly· 1 shared A. R. Venkitaraman· 1 shared C. Abell· 1 shared C. Valenzano· 1 shared D. E. Scott· 1 shared D. J. Huggins· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Esposito

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1 paper

Recent·Most cited

Cancer BiologybioRxivJul 15, 2020

A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death

D. E. Scott, N. J. Francis-Newton, M. E. Marsh…·C. Abell

The paper identifies CAM833, a small-molecule inhibitor of BRCA2-RAD51 interaction, which disrupts RAD51 assembly and enhances DNA damage-induced cell death in BRCA2-wildtype cells.

DOI 10.1016/j.chembiol.2021.02.006

humanexperimental assay

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