Author

N. Juge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Bell· 2 shared E. SEVERI· 2 shared G. H. Thomas· 2 shared T. Palmer· 2 shared A. Ana Martinez Gascuena· 1 shared A. Lee· 1 shared A. Pal· 1 shared A. Parris· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

A. Bell

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Characterisation of anhydro-sialic acid transporters from mucosa-associated bacteria

Y. Wu, A. Bell, G. H. Thomas, D. N. Bolam, F. Sargent, N. Juge, T. Palmer, E. SEVERI

The paper identifies and characterizes anhydro-sialic acid transporters in bacteria, showing their specific or promiscuous substrate preferences.

bioRxiv · Jan 17, 2024Microbiology

Sialidases and Fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria

B. Shuoker, M. J. Pichler, C. Jin, H. Sakanaka, H. Wu, A. Ana Martinez Gascuena, J. Liu, T. S. Nielsen, J. Holgersson, E. Nordberg Karlsson, N. Juge, S. Meier, J. P. Morth, N. G. Karlsson, M. Abou Hachem

This study identifies sialidases and fucosidases in Akkermansia muciniphila that degrade mucin glycans and enable nutrient sharing with gut bacteria.

bioRxiv · Sep 10, 2022 · PreprintBiochemistry

Guardian crypt-base-goblet-cells protect the human colonic stem cell niche by triggering cholinergic calcium signal-dependent MUC2 secretion and luminal flushing

N. Pelaez-Llaneza, V. Jones, C. Kam, A. Lee, A. Parris, S. Tattan, M. Loader, J. Champion, G. Russam, B. Miller, N. Juge, R. Wharton, C. Speakman, S. Kapur, J. Hernon, , M. R. Williams

The paper identifies a mechanism by which cholinergic calcium signals in colonic stem cell niches trigger MUC2 secretion and luminal flushing.

bioRxiv · Jan 4, 2022 · PreprintCell Biology

Multiple evolutionary origins reflect the importance of sialic acid transporters in the colonisation potential of bacterial pathogens and commensals.

E. Severi, M. Rudden, A. Bell, T. Palmer, N. Juge, G. H. Thomas

This study identifies multiple evolutionary origins of sialic acid transporters in bacteria, highlighting their role in host-microbe interactions and microbial colonization.

bioRxiv · Mar 1, 2021Microbiology