The wtf4 meiotic driver utilizes controlled protein aggregation to generate selective cell death
N. L. Nuckolls, A. C. Mok, J. J. Lange, K. Yi, T. S. Kandola, A. M. Hunn, S. McCroskey, J. L. Snyder, M. A. Bravo Nunez, M. McClain, S. A. McKinney, C. Wood, R. Halfmann, S. E. Zanders
This study shows that the wtf4 meiotic driver uses protein aggregation and sequestration to selectively kill cells, revealing a mechanism for meiotic drive.
bioRxiv · Feb 5, 2020Cell Biology