BiophysicsbioRxiv
Mechanistic inferences from analysis of measurements of protein phase transitions in live cells
A. E. Posey, K. M. Ruff, J. M. Lalmansingh…·R. V. Pappu
This paper develops a supervised method to classify phase transitions in live cells using DAmFRET data, revealing sequence features that drive prion-like behavior and enabling quantitative analysis of nucleation probabilities.
DOI 10.1016/j.jmb.2021.166848