Author

N. Legrand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Ianevski· 2 shared D. E. Kainov· 2 shared E. Zusinaite· 2 shared G. Grodeland· 2 shared H. Lysvand· 2 shared M. Bjoras· 2 shared T. Tenson· 2 shared V. Oksenych· 2 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

A. Ianevski

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Nafamostat-interferon-alpha combination suppresses SARS-CoV-2 infection by targeting cooperatively host TMPRSS2 in vitro and in vivo

A. Ianevski, R. Yo, H. Lysvand, G. Grodeland, N. Legrand, V. Oksenych, E. Zusinaite, T. Tenson, M. Bjoras, D. E. Kainov

This study combines nafamostat and interferon-alpha to suppress SARS-CoV-2 infection by targeting TMPRSS2 in vitro and in vivo.

bioRxiv · Jun 16, 2021Microbiology

Interferon alpha-based combinations suppress SARS-CoV-2 infection in vitro and in vivo

A. Ianevski, R. Yao, E. Zusinaite, L. S. Lello, S. Wang, E. Jo, J. Yang, E. Ravlo, W. Wang, H. Lysvand, K. Loseth, V. Oksenych, T. Tenson, M. P. Windisch, M. Poranen, , D. E. Kainov

This study shows that IFNa-based combinations effectively inhibit SARS-CoV-2 infection in vitro and in vivo, with synergistic effects against other viruses.

bioRxiv · Jan 5, 2021 · PreprintMicrobiology