Author

N. Lowe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:Drosophila· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

A. V. Kolesov· 1 shared A.-C. Sayadian· 1 shared C. Slawson· 1 shared D. Na· 1 shared D. St Johnston· 1 shared D. T. Bergstralh· 1 shared H. Fedosyuk· 1 shared H. J. O'Toole· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperBiophysics

A. V. Kolesov

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Plasma-derived extracellular vesicles (EVs) as biomarkers of sepsis in burn patients via label-free Raman spectroscopy

H. J. O'Toole, N. Lowe, V. Arun, A. V. Kolesov, T. L. Palmieri, N. K. Tran, R. P. Carney

This study uses Raman spectroscopy to detect sepsis in burn patients by analyzing plasma-derived extracellular vesicles, achieving high sensitivity and specificity.

bioRxiv · May 14, 2024Biophysics

The spindle orienting machinery requires activation, not just localization

K. E. Neville, T. M. Finegan, N. Lowe, P. M. Bellomio, D. Na, D. T. Bergstralh

This study shows that spindle orientation requires both Pins localization and activation, with Discs large mediating activation, challenging the canonical model that only localization determines orientation.

EMBO Reports · Mar 6, 2023Peer-reviewedCell Biology

Repurposing the CRISPR-Cas9 System for Targeted Chromatin O-linked β-N- acetylglucosamine Editing

M. P. Parker, W. B. Dias, W. Brautman, N. Lowe, H. Fedosyuk, K. R. Peterson, C. Slawson

This paper develops a CRISPR-Cas9-based system to manipulate O-GlcNAc modification at cis-regulatory elements, demonstrating its role in γ-globin gene regulation.

bioRxiv · Oct 27, 2022 · PreprintBiochemistry

An alternative mode of epithelial polarity in the Drosophila midgut

J. Chen, A.-C. Sayadian, N. Lowe, H. Lovegrove, D. St Johnston

The paper shows that Drosophila midgut epithelia polarize without canonical polarity factors, using integrin adhesion instead, suggesting conserved diversity in polarity mechanisms across species.

bioRxiv · Apr 24, 2018Cell Biology