Author

W. B. Dias

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. R. Todeschini· 3 shared A. C. C. Valim· 1 shared A. Carlos Fonseca· 1 shared A. F. Dias· 1 shared A. Filardy· 1 shared A. Zippelius· 1 shared C. B. V. Andrade· 1 shared C. de Souza Bastos· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersPhysiology

A. R. Todeschini

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Sex-specific effect of antenatal Zika virus infection on murine fetal growth, placental nutrient transporters, and nutrient sensor signaling pathways

D. Pereira-Carvalho, A. C. C. Valim, C. B. V. Andrade, E. Bloise, A. F. Dias, V. M. O. Nascimento, R. K. Silva Alves, F. Lopes Brum, I. G. Medeiros, S. V. A. Coelho, L. B. Arruda, A. R. Todeschini, W. B. Dias, T. M. Ortiga-Carvalho

This study investigates how maternal Zika virus infection affects placental nutrient transporters and signaling pathways differently in male and female fetuses, revealing sex-specific molecular alterations in nutrient handling.

The FASEB Journal · Jul 9, 2024Peer-reviewedPhysiology

Repurposing the CRISPR-Cas9 System for Targeted Chromatin O-linked β-N- acetylglucosamine Editing

M. P. Parker, W. B. Dias, W. Brautman, N. Lowe, H. Fedosyuk, K. R. Peterson, C. Slawson

This paper develops a CRISPR-Cas9-based system to manipulate O-GlcNAc modification at cis-regulatory elements, demonstrating its role in γ-globin gene regulation.

bioRxiv · Oct 27, 2022 · PreprintBiochemistry

Updates on enzymatic and structural properties of human glutamine: fructose-6-phosphate amidotransferase 2 (hGFAT2)

I. A. Oliveira, D. Allonso, T. V. A. Fernandes, D. M. S. Lucena, G. T. Ventura, W. B. Dias, R. Mohana-Borges, P. G. Pascutti, A. R. Todeschini

This study reports the expression, purification, and characterization of hGFAT2, revealing its unique enzymatic properties and structural features.

bioRxiv · Jul 13, 2020 · PreprintBiochemistry

Hyperglycemia enhances cancer immune evasion by inducing alternative macrophage polarization through increased O-GlcNAcylation

N. Rodrigues Mantuano, M. A. Stanczak, I. de Araujo Oliveira, N. Kirchhammer, A. Filardy, G. Monaco, R. C. Santos, A. Carlos Fonseca, M. Fontes, C. de Souza Bastos, W. B. Dias, A. Zippelius, A. R. Todeschini, H. Laubli

This study shows hyperglycemia promotes cancer immune evasion by increasing O-GlcNAcylation in tumor-associated macrophages, shifting their polarization to a pro-tumorigenic M2-like phenotype.

bioRxiv · Nov 5, 2019Cancer Biology