Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
7 papers
Recent·Most cited
S. Boyd, D. Robarts, K. Nguyen, M. Villar, I. Alghusen, M. Kotulkar, A. Denson, H. Fedoosyuk, N. Lee, S. A. Whelan, J. A. Hanover, W. Dias, E. P. Tan, S. McGreal, A. Artigues, , C. Slawson
The paper uses multi-omics analysis to show OGT regulates aneuploidy by fine-tuning multiple cellular pathways through O-GlcNAcylation.
bioRxiv · Apr 16, 2024 · PreprintCell Biology
D. R. Robarts, M. Kotulkar, D. Paine-Cabrera, K. K. Venneman, J. A. Hanover, N. E. Zachara, C. Slawson, U. Apte
This study shows that O-GlcNAcylation is essential for hepatocyte differentiation and its loss promotes liver fibrosis and hepatocellular carcinoma.
bioRxiv · Feb 16, 2023Pathology
M. P. Parker, W. B. Dias, W. Brautman, N. Lowe, H. Fedosyuk, K. R. Peterson, C. Slawson
This paper develops a CRISPR-Cas9-based system to manipulate O-GlcNAc modification at cis-regulatory elements, demonstrating its role in γ-globin gene regulation.
bioRxiv · Oct 27, 2022 · PreprintBiochemistry
D. R. Robarts, S. R. McGreal, D. S. Umbaugh, W. S. Parkes, M. Kotulkar, S. Abernathy, N. Lee, H. Jaeschke, S. Gunewardena, S. A. Whelan, J. A. Hanover, N. E. Zachara, C. Slawson, U. Apte
This study shows that O-GlcNAcylation in hepatocytes is essential for proper liver regeneration, with its loss leading to uncontrolled proliferation and tumor formation.
bioRxiv · Oct 14, 2021Pathology
N. Sharma, V. K. Gupta, P. Dauer, K. Kesh, R. Hadad, B. Giri, A. Chandra, V. Dudeja, C. Slawson, S. Banerjee, S. M. Vickers, A. Saluja, S. Banerjee
This study shows that O-GlcNAc modification of Sox2 stabilizes the protein and enhances self-renewal in pancreatic cancer, with targeting OGT reducing tumor burden.
bioRxiv · Jun 12, 2018Cancer Biology
Z. Zhang, M. P. Parker, S. Graw, L. Novikova, H. Fedosyuk, J. Fontes, D. Koestler, K. Peterson, C. Slawson
This study shows that O-GlcNAc homeostasis regulates cell fate decisions in hematopoiesis by affecting transcriptional programs and differentiation outcomes.
bioRxiv · Jun 4, 2018Biochemistry
M. Machacek, Z. Zhang, E. P. Tan, J. Li, T. Li, M. T. Villar, A. Artigues, T. Lydic, C. Slawson, P. Fields
The paper shows that elevated O-GlcNAcylation in CD4+ T cells enhances Th17 function by altering the lipid microenvironment, increasing IL-17A production in obesity.
bioRxiv · Apr 20, 2018Immunology