SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation
J.-H. Choi, X. Zhang, C. Zhang, D. L. Dai, J. Luo, R. Ladak, Q. Li, S. Wiebe, A. C. H. Liu, X. Ran, J. Yang, P. Naeli, A. Garzia, L. Zhou, N. Mahmood, , N. Sonenberg
This study identifies NSP2-induced repression of Ifnb1 mRNA translation as a mechanism by which SARS-CoV-2 suppresses IFN-β production.
bioRxiv · Jan 19, 2022 · PreprintMicrobiology