Age-associated sleep-wake patterns are altered with Prdm13 signaling in the dorsomedial hypothalamus and dietary restriction in mice
S. Tsuji, C. S. Brace, R. Yao, Y. Tanie, H. Tada, N. Rensing, S. Mizuno, J. Almunia, Y. Kong, K. Nakamura, N. Ogiso, S. Toyokuni, S. Takahashi, M. Wong, S.-i. Imai, A. Satoh
This study shows that Prdm13 signaling in the dorsomedial hypothalamus affects age-related sleep-wake changes in mice, and dietary restriction can mitigate these effects.
bioRxiv · Sep 26, 2022 · PreprintPhysiology