S. Tsuji

A novel VCP modulator, KUS121, attenuates atherosclerosis progression by maintaining intracellular ATP and mitigating ER stress in endothelial cells

This study shows that KUS121 reduces atherosclerosis by maintaining ATP levels and reducing ER stress in endothelial cells.

Assessing the potential of eDNA analysis for spawning surveys in marine environments: A case study on Japanese jack mackerel

This study assesses eDNA analysis for marine spawning surveys, finding that eDNA concentrations peak during the spawning season of Japanese jack mackerel, confirming spawning activity through time-series sampling and plankton net egg collection.

An engineered ACE2 decoy broadly neutralizes Omicron subvariants and shows therapeutic effect in SARS-CoV-2-infected cynomolgus macaques

This paper shows an engineered ACE2 decoy neutralizes Omicron subvariants and is effective in treating SARS-CoV-2 infection in macaques.

Age-associated sleep-wake patterns are altered with Prdm13 signaling in the dorsomedial hypothalamus and dietary restriction in mice

This study shows that Prdm13 signaling in the dorsomedial hypothalamus affects age-related sleep-wake changes in mice, and dietary restriction can mitigate these effects.

Quantitative environmental DNA metabarcoding shows high potential as a novel approach to quantitatively assess fish community

This study evaluates the qMiSeq approach for quantitative eDNA metabarcoding to assess fish communities by comparing eDNA concentrations with capture survey results.

Differences in the genetic structure between and within two landlocked Ayu groups with different migration patterns in Lake Biwa revealed by environmental DNA analysis

This study uses environmental DNA analysis to reveal genetic differences between two landlocked Ayu groups in Lake Biwa based on migration patterns and geographical distance.

Analysis of the persistence and particle size distributional shift of sperm-derived environmental DNA to monitor Jack Mackerel spawning activity

This study investigates the persistence and particle size distribution of sperm-derived eDNA from Japanese jack mackerel to better monitor spawning activity.

Metabolic flux and flux balance analyses indicate the relevance of metabolic thermogenesis and aerobic glycolysis in cancer cells

The paper uses metabolic flux analysis to show that cancer cells prefer aerobic glycolysis over oxidative phosphorylation due to reduced metabolic heat generation.