Author

N. R. Brady

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Assay:imaging· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Hamacher-Brady· 2 shared I. Coppens· 2 shared A. Casadevall· 1 shared C. Coelho· 1 shared E. S. Nakayasu· 1 shared G. Lauvau· 1 shared H. M. Heyman· 1 shared J. E. Kyle· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

A. Hamacher-Brady

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Author profile →

2 papers

Recent·Most cited

XIAP-mediated targeting of endolysosomes to stressed mitochondria occurs in a switch-like, global manner and results in autophagy-independent, sub-organelle level mitochondrial degradation

T. S. Wang, I. Coppens, N. R. Brady, A. Hamacher-Brady

The paper shows XIAP mediates rapid, global endolysosome targeting to stressed mitochondria, leading to sub-organelle degradation independent of autophagy.

bioRxiv · Apr 23, 2023 · PreprintCell Biology

Listeria monocytogenes virulence factors are secreted in biologically active Extracellular Vesicles

C. Coelho, L. Brown, M. Maryam, M. C. Burnet, J. E. Kyle, H. M. Heyman, R. Vij, J. Ramirez, R. Prados-Rosales, G. Lauvau, E. S. Nakayasu, N. R. Brady, A. Hamacher-Brady, I. Coppens, A. Casadevall

This study shows Listeria monocytogenes secretes biologically active extracellular vesicles containing virulence factors like LLO and PI-PLC, which contribute to cytotoxicity in macrophages.

bioRxiv · Jan 20, 2018Microbiology