R. Prados-Rosales

This study identifies LamH, a glycoside hydrolase that cleaves -1,6-mannoside linkages in LAM/LM, enabling their export to the capsule and promoting bacterial growth.

The paper identifies TLR8 as a key regulator of intracellular killing of Mtb, showing that phagosomal RNA sensing through TLR8 controls susceptibility to tuberculosis and reveals a druggable pathway for host-directed therapy.

This study identifies dynamin-like proteins IniA and IniC as essential for extracellular vesicle biogenesis in Mycobacterium tuberculosis under iron limitation and VirR restriction.

This study identifies the structural unit of melanin in the fungal pathogen Cryptococcus neoformans, revealing its organization into nanospheres and granules.

This study shows Listeria monocytogenes secretes biologically active extracellular vesicles containing virulence factors like LLO and PI-PLC, which contribute to cytotoxicity in macrophages.