Author

N. Rohatgi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

U. Ghoshdastider· 2 shared A. J. Skanderup· 1 shared A. Jacobsen Skanderup· 1 shared A. Wong· 1 shared B. Chowbay· 1 shared E. Revkov· 1 shared G. Mbalaviele· 1 shared H. Yan· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

U. Ghoshdastider

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Tmem178 negatively regulates IL-1β production through inhibition of the NLRP3 inflammasome

K. Khanna, H. Yan, M. Mehra, N. Rohatgi, G. Mbalaviele, R. Faccio

This study identifies Tmem178 as a negative regulator of IL-1β production by inhibiting the NLRP3 inflammasome in macrophages, with implications for sJIA and CSS.

bioRxiv · Mar 7, 2023Immunology

A pan-cancer metabolic atlas of the tumor microenvironment

N. Rohatgi, U. Ghoshdastider, P. Baruah, A. J. Skanderup

The paper profiles metabolic states of cancer and stromal cells across 20 solid tumors, identifying pan-cancer metabolic patterns and stromal immune suppression mechanisms.

bioRxiv · Oct 16, 2020Cancer Biology

Data-driven inference of crosstalk in the tumor microenvironment

U. Ghoshdastider, M. M. Naeini, N. Rohatgi, E. Revkov, A. Wong, S. Solai, T. T. Nguyen, J. Yeong, J. Iqbal, P. H. Tan, B. Chowbay, R. DasGupta, A. Jacobsen Skanderup

The paper develops a data-driven method to deconvolute bulk tumor transcriptomes and predict cancer-stromal crosstalk in 20 solid tumor types, revealing new insights into signaling patterns.

bioRxiv · Jun 15, 2020 · PreprintCancer Biology