SLC17 transporters mediate renal excretion of Lac-Phe in mice and humans
V. L. Li, S. Xiao, P. Schlosser, N. Scherer, A. L. Wiggenhorn, J. Spaas, A. S.-H. Tung, E. D. Karoly, A. Kottgen, J. Z. Long
This study identifies SLC17A1 and SLC17A3 as key transporters for Lac-Phe excretion in urine, showing genetic and functional associations in mice and humans.
bioRxiv · Apr 18, 2024 · PreprintBiochemistry