Functional analysis of flavivirus replicase by deep mutational scanning of dengue NS5
A. Suphatrakul, P. Posiri, N. Srisuk, R. Nantachokchawapan, S. Onnome, J. Mongkolsapaya, B. Siridechadilok
The paper uses deep mutational scanning to analyze dengue virus NS5, identifying conserved residues and potential plasticity in its replicase activity, with implications for antiviral strategies.
bioRxiv · Mar 7, 2023 · PreprintMicrobiology