S. Hongeng

Red blood cell-derived extracellular vesicles with miR-204 mimic loading for pediatric neuroblastoma treatment

This study develops red blood cell-derived extracellular vesicles loaded with miR-204 mimic to treat neuroblastoma, showing inhibitory effects on cell viability and spheroid growth.

Broad neutralization of SARS-CoV-2 variants by circular mRNA producing VFLIP-X spike in mice

This study shows that a circular mRNA vaccine encoding VFLIP-X spike protein induces broad neutralizing antibodies against SARS-CoV-2 variants in mice.

An integrative approach leads to the discovery of a novel anti-leukemic peptide from human milk

This paper discovers a novel anti-leukemic peptide, HMP-S7, from human breast milk through an integrative approach involving mass spectrometry, in silico screening, and in vitro testing.

Mice immunized with the vaccine candidate HexaPro spike produce neutralizing antibodies against SARS-CoV-2

This study shows that mice vaccinated with HexaPro spike protein produce high-titer neutralizing antibodies against SARS-CoV-2 for up to 56 days.

Anti-SARS-CoV-2 activity of Andrographis paniculata extract and its major component Andrographolide in human lung epithelial cells and cytotoxicity evaluation in major organ cell representatives

This study evaluates the anti-SARS-CoV-2 activity of Andrographis paniculata extract and andrographolide in human lung cells and assesses their cytotoxicity across organ-specific cell lines.

Potent programmable antiviral against dengue virus in primary human cells by Cas13b RNP with short spacer and delivery by virus-like particle

This study demonstrates that PspCas13b RNP delivered by virus-like particles can efficiently suppress dengue virus infection in primary human cells using short spacers.