Author

N. Ventura

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Schiavi· 2 shared A. Kar· 1 shared A. Shaik· 1 shared A. Villanueva· 1 shared B. Herron· 1 shared B. L. Kennedy· 1 shared C. Martinez-Fernandez· 1 shared D. Brena· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersBiochemistry

A. Schiavi

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Author profile →

4 papers

Recent·Most cited

Up-regulation of cholesterol synthesis by lysosomal defects requires a functional mitochondrial respiratory chain

F. Agostini, L. Pereyra, J. Dale, K. F. Yambire, S. Maglioni, A. Schiavi, N. Ventura, I. Milosevic, N. Raimundo

The paper identifies that lysosomal defects up-regulate cholesterol synthesis via mitochondrial respiratory chain interactions and Ca2+ retention, while mitochondrial defects down-regulate it.

bioRxiv · Mar 6, 2024Biochemistry

Inhibition of ATR Reverses a Mitochondrial Respiratory Insufficiency

M. B. Borror, M. Girotti, A. Kar, M. Cain, X. Gao, V. MacKay, B. Herron, S. Bhaskaran, S. Becerra, N. Novy, N. Ventura, T. E. Johnson, B. L. Kennedy, S. L. Rea

This study shows that inhibiting ATR in C. elegans reduces the severity of mitochondrial ETC dysfunction by reversing nucleotide imbalances and restoring translation.

Cells · May 24, 2022Peer-reviewedPathology

Insights into cisplatin-induced neurotoxicity and mitochondrial dysfunction in Caenorhabditis elegans

C. Martinez-Fernandez, M. Bergamino, D. Brena, N. Ventura, S. Honnen, A. Villanueva, E. Nadal, J. Ceron

This study investigates cisplatin-induced neurotoxicity and mitochondrial dysfunction in C. elegans using genetic, biochemical, and behavioral assays.

bioRxiv · Jun 3, 2021Cell Biology

Ahr-bacterial diet interaction modulates aging and associated pathologies in C. elegans

V. Brinkmann, A. Schiavi, A. Shaik, D. R. Puchta, N. Ventura

This paper shows that C. elegans AHR-1 modulates aging and age-related pathologies through interactions with bacterial diet metabolites, establishing C. elegans as a model for studying AhR functions.

bioRxiv · Apr 13, 2020Physiology