Author

N. Waddell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. A. Jungbluth· 1 shared A. Baggiolini· 1 shared A. DeFazio· 1 shared A. Dobrovic· 1 shared A. Kane· 1 shared A. Musafer· 1 shared A.-M. Patch· 1 shared B. Leggett· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

A. A. Jungbluth

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Author profile →

3 papers

Recent·Most cited

Acquired RAD51C promoter methylation loss causes PARP inhibitor resistance in high grade serous ovarian carcinoma

K. Nesic, O. Kondrashova, R. M. Hurley, C. McGehee, C. J. Vandenberg, G.-Y. Ho, E. Lieschke, G. Dall, N. Bound, K. Shield-Artin, M. R. Radke, A. Musafer, Z. Qing Chai, M. R. Eftekhariyan Ghamsari, M. I. Harrell, , C. L. Scott

This study shows that loss of RAD51C promoter methylation leads to PARP inhibitor resistance in high-grade serous ovarian carcinoma, independent of BRCA1 methylation status.

bioRxiv · Dec 10, 2020Cancer Biology

Anatomic position determines oncogenic specificity in melanoma

J. M. Weiss, M. V. Hunter, N. M. Cruz, A. Baggiolini, M. Tagore, Y. Ma, S. Misale, M. Marasco, T. Simon-Vermot, N. R. Campbell, F. Newell, J. S. Wilmott, P. A. Johansson, J. F. Thompson, G. V. Long, , R. M. White

The paper shows that anatomic position influences oncogenic specificity in melanoma by identifying position-specific gene programs that interact with oncogenes like CRKL.

bioRxiv · Nov 14, 2020Cancer Biology

APC Mutation marks an aggressive subtype of BRAF mutant colorectal cancers

L. Fennell, A. Kane, C. Liu, D. Mckeone, W. Fernando, C. Su, C. Bond, S. Jamieson, T. Dumenil, A.-M. Patch, S. Kazakoff, J. Pearson, N. Waddell, B. Leggett, V. Whitehall

This study identifies APC mutations as a marker of aggressive BRAF mutant colorectal cancers, associated with poor prognosis and enhanced tumor growth in mouse models.

bioRxiv · Feb 16, 2020Cancer Biology