Author

N. Y. R. Agar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Approach:microscopy & imaging analysis· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

M. C. Haigis· 2 shared S. A. Stopka· 2 shared A. C. Wang· 1 shared A. Clermont· 1 shared A. Dean· 1 shared A. Janzer· 1 shared A. Ringel· 1 shared A. Sutter· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

M. C. Haigis

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Author profile →

3 papers

Recent·Most cited

BiochemistrybioRxivPreprintDec 13, 2021

Characterization of metabolic compartmentalization in the liver using spatially resolved metabolomics

J. van der Reest, S. A. Stopka, W. M. Abdelmoula…·N. Y. R. Agar

This study uses spatially resolved metabolomics to characterize metabolic compartmentalization in the liver and shows how nutrient stress disrupts this organization.

DOI 10.1101/2021.12.13.472421

mousemetabolomics

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Cancer BiologybioRxivNov 30, 2021

De Novo Pyrimidine Synthesis is a Targetable Vulnerability in IDH Mutant Glioma

D. D. Shi, M. R. Savani, M. M. Levitt…·McBray

This study identifies de novo pyrimidine synthesis as a therapeutic target in IDH mutant gliomas, showing that DHODH inhibitors are effective in preclinical models.

DOI 10.1016/j.ccell.2022.07.011

mouseexperimental assay

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Cell BiologybioRxivPreprintSep 29, 2019

PHD3 controls energy homeostasis and exercise capacity.

H. Yoon, J. B. Spinelli, E. Zaganjor…·M. C. Haigis

The paper was submitted in error and the authors do not wish it to be cited.

DOI 10.1101/781765

𝕏 PostBluesky