Enhancer connectome in primary human cells reveals target genes of disease-associated DNA elements
Maxwell R. Mumbach, Ansuman T. Satpathy, Evan A. Boyle, Chao Dai, Benjamin G. Gowen, Seung Woo Cho, Michelle Ly Thai Nguyen, Adam J. Rubin, Jeffrey M. Granja, Katelynn R. Kazane, Yuning Wei, Trieu Nguyen, Peyton Greenside, M. Ryan Corces, Josh Tycko, , Howard Y. Chang
This paper uses HiChIP to map enhancer-promoter interactions in primary human cells, linking disease-associated DNA variants to their target genes.
Nature Genetics · Sep 25, 2017Peer-reviewedGenomics